Therapeutic Potential of Targeting the Th17/Treg Axis in Autoimmune Disorders

A disruption of the crucial balance between regulatory T-cells (Tregs) and Th17-cells was recently implicated in various autoimmune disorders. Tregs are responsible for the maintenance of self-tolerance, thus inhibiting autoimmunity, whereas pro-inflammatory Th17-cells contribute to the induction an...

Full description

Bibliographic Details
Main Authors: Patrizia Fasching, Martin Stradner, Winfried Graninger, Christian Dejaco, Johannes Fessler
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/1/134