Purine nucleoside analog--sulfinosine modulates diverse mechanisms of cancer progression in multi-drug resistant cancer cell lines.

Achieving an effective treatment of cancer is difficult, particularly when resistance to conventional chemotherapy is developed. P-glycoprotein (P-gp) activity governs multi-drug resistance (MDR) development in different cancer cell types. Identification of anti-cancer agents with the potential to k...

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Bibliographic Details
Main Authors: Mirjana Dačević, Aleksandra Isaković, Ana Podolski-Renić, Andelka M Isaković, Tijana Stanković, Zorica Milošević, Ljubisav Rakić, Sabera Ruždijić, Milica Pešić
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3543365?pdf=render