A genome-wide screen identifies a single β-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins

<p>Abstract</p> <p>Background</p> <p>Defensins comprise a large family of cationic antimicrobial peptides that are characterized by the presence of a conserved cysteine-rich defensin motif. Based on the spacing pattern of cysteines, these defensins are broadly divided i...

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Bibliographic Details
Main Authors: Xiao Yanjing, Hughes Austin L, Ando Junko, Matsuda Yoichi, Cheng Jan-Fang, Skinner-Noble Donald, Zhang Guolong
Format: Article
Language:English
Published: BMC 2004-08-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/5/56