Optogenetics reveals a role for accumbal medium spiny neurons expressingdopamine D2 receptors in cocaine-induced behavioral sensitization

Optogenetics reveals a role for accumbal medium spiny neurons expressingdopamine D2 receptors in cocaine-induced behavioral sensitization

Long-lasting, drug-induced adaptations within the nucleus accumbens (NAc) have beenproposed to contribute to drug-mediated addictive behaviors. Here we have used anoptogenetic approach to examine the role of NAc medium spiny neurons (MSNs) expressingdopamine D2 receptors (D2R) in cocaine-induced beh...

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Bibliographic Details
Main Authors: Shelly Sooyun eSong, Byeong Jun eKang, Lei eWen, Hyo Jin eLee, Hye-ri eSim, Tae Hyong eKim, Sehyoun eYoon, Bong-June eYoon, George J eAugustine, Ja-Hyun eBaik
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Cocaine
drug addiction
optogenetics
Medium spiny neurons
dopamine D2 receptors
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00336/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00336/full

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