Collagen XVII Processing and Blistering Skin Diseases

Collagen XVII (COL17) is a hemidesmosomal transmembrane protein in the skin, which, in several autoimmune blistering skin diseases, may be targeted by autoantibodies. In addition, loss-of-function mutations in the COL17A1 gene induce a subtype of junctional epidermolysis bullosa. The extracellular d...

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Bibliographic Details
Main Author: Wataru Nishie
Format: Article
Language:English
Published: Society for Publication of Acta Dermato-Venereologica 2020-02-01
Series:Acta Dermato-Venereologica
Subjects:
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-3399