Epigenetic Regulation of Apoptosis and Cell Cycle in Osteosarcoma

The role of genetic mutations in the development of osteosarcoma, such as alterations in p53 and Rb, is well understood. However, the significance of epigenetic mechanisms in the progression of osteosarcoma remains unclear and is increasingly being investigated. Recent evidence suggests that epigene...

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Bibliographic Details
Main Authors: Krithi Rao-Bindal, Eugenie S. Kleinerman
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2011/679457