DUX4 differentially regulates transcriptomes of human rhabdomyosarcoma and mouse C2C12 cells.

Facioscapulohumeral muscular dystrophy (FSHD) is linked to the deletion of the D4Z4 arrays at chromosome 4q35. Recent studies suggested that aberrant expression of double homeobox 4 (DUX4) from the last D4Z4 repeat causes FSHD. The aim of this study is to determine transcriptomic responses to ectopi...

Full description

Bibliographic Details
Main Authors: Vishakha Sharma, Naoe Harafuji, Alexandra Belayew, Yi-Wen Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3661531?pdf=render