Polymorphisms in genes of interleukin 12 and its receptors and their association with protection against severe malarial anaemia in children in western Kenya

<p>Abstract</p> <p>Background</p> <p>Malarial anaemia is characterized by destruction of malaria infected red blood cells and suppression of erythropoiesis. Interleukin 12 (IL12) significantly boosts erythropoietic responses in murine models of malarial anaemia and decr...

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Main Authors: Slutsker Laurence, Lal Altaf A, Terlouw Dianne, Nahlen Bernard, Kariuki Simon, ter Kuile Feiko, Crawford Sara, Eng Jodi, Prather Donald, Zhang Lyna, Udhayakumar Venkatachalam, Shi Ya
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/9/1/87