Identification of IGF-1-enhanced cytokine expressions targeted by miR-181d in glioblastomas via an integrative miRNA/mRNA regulatory network analysis

Identification of IGF-1-enhanced cytokine expressions targeted by miR-181d in glioblastomas via an integrative miRNA/mRNA regulatory network analysis

Abstract The insulin-like growth factor (IGF)-1 signaling is relevant in regulating cell growth and cytokine secretions by glioblastomas. MicroRNAs determine the cell fate in glioblastomas. However, relationships between IGF-1 signaling and miRNAs in glioblastoma pathogenesis are still unclear. Our...

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Bibliographic Details
Main Authors: Kuo-Hao Ho, Peng-Hsu Chen, Edward Hsi, Chwen-Ming Shih, Wei-Chiao Chang, Chia-Hsiung Cheng, Cheng-Wei Lin, Ku-Chung Chen
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00826-0

Internet

https://doi.org/10.1038/s41598-017-00826-0

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