Celebrating 20 Years of IGHV Mutation Analysis in CLL

Abstract. The division of CLL into 2 broad subsets with highly significant differences in clinical behavior was reported in 2 landmark papers in Blood in 1999.1,2 The simple analysis of the mutational status of the IGV regions provided both a prognostic indicator and an insight into the cellular ori...

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Bibliographic Details
Main Authors: Nicholas Chiorazzi, Freda K. Stevenson
Format: Article
Language:English
Published: Wolters Kluwer 2020-02-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000334