Intervertebral disc and endplate cells response to IL-1β inflammatory cell priming and identification of molecular targets of tissue degeneration

Inflammation represents an important factor leading to metabolic imbalance within the intervertebral disc (IVD), conducive to degenerative changes. Therefore, a thorough knowledge of the IVD and endplate (EP) cell behaviour in such pathological environments is essential when designing regenerative t...

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Bibliographic Details
Main Authors: P De Luca, L de Girolamo, D Kouroupis, M Castagnetta, C Perucca Orfei, D Coviello, S Coco, D Correa, M Brayda-Bruno, A Colombini
Format: Article
Language:English
Published: AO Research Institute Davos 2020-06-01
Series:European Cells & Materials
Subjects:
Online Access:https://www.ecmjournal.org/papers/vol039/pdf/v039a15.pdf