Inhibitory action of azelastine hydrochloride on the induction of mast cells from normal mouse splenocytes

Inhibitory action of azelastine hydrochloride on the induction of mast cells from normal mouse splenocytes

The influence of azelastine (AZ) on murine mast cell induction was examined by in vitro cell culture techniques. Splenocytes from normal BALB/c mice suspended in RPMI-1640 medium supplemented with interleukin-3 were cultured in the presence or absence of AZ. The number of mast cells increased gradua...

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Bibliographic Details
Main Authors: Kazuhito Asano, Masashi Taki, Sumitaka Matsuo, Kaneo Yamada
Format: Article
Language:English
Published: Elsevier 1997-01-01
Series:Allergology International
Subjects:
apoptosis
azelastine
in vitro mast cell growth
Correspondence: Dr K Asano
Department of Medical Biology
School of Medicine
Showa University
1-5-8 Hatanodai
Shinagawa-ku
Tokyo 142
Japan
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015316087

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http://www.sciencedirect.com/science/article/pii/S1323893015316087

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