Pleiotropic Effects of PCSK-9 Inhibitors

Pleiotropic Effects of PCSK-9 Inhibitors

Proprotein convertase subtilisin/kexin type 9 (PCSK-9) inhibitors are a group of drugs whose main mechanism of action is binding to the PCSK-9 molecule, which reduces the degradation of the low-density lipoprotein receptor (LDL-R) and, hence, increases the uptake of low-density lipoprotein cholester...

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Bibliographic Details
Main Authors: Marcin Basiak, Michał Kosowski, Marcin Cyrnek, Łukasz Bułdak, Mateusz Maligłówka, Grzegorz Machnik, Bogusław Okopień
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
pleiotropic effects
PCSK-9
anti-atherosclerotic effect
anti-aggregation effect
anticoagulant effect
antineoplastic effect
Online Access:https://www.mdpi.com/1422-0067/22/6/3144

Internet

https://www.mdpi.com/1422-0067/22/6/3144

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