Escherichia coli with a Tunable Point Mutation Rate for Evolution Experiments

The mutation rate and mutations’ effects on fitness are crucial to evolution. Mutation rates are under selection due to linkage between mutation rate modifiers and mutations’ effects on fitness. The linkage between a higher mutation rate and more beneficial mutations selects for higher mutation rate...

Full description

Bibliographic Details
Main Authors: Nicholas A. Sherer, Thomas E. Kuhlman
Format: Article
Language:English
Published: Oxford University Press 2020-08-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.120.401124