Creatine Prevents the Structural and Functional Damage to Mitochondria in Myogenic, Oxidatively Stressed C2C12 Cells and Restores Their Differentiation Capacity

Creatine (Cr) is a nutritional supplement promoting a number of health benefits. Indeed Cr has been shown to be beneficial in disease-induced muscle atrophy, improve rehabilitation, and afford mild antioxidant activity. The beneficial effects are likely to derive from pleiotropic interactions. In ac...

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Bibliographic Details
Main Authors: Elena Barbieri, Michele Guescini, Cinzia Calcabrini, Luciana Vallorani, Anna Rita Diaz, Carmela Fimognari, Barbara Canonico, Francesca Luchetti, Stefano Papa, Michela Battistelli, Elisabetta Falcieri, Vanina Romanello, Marco Sandri, Vilberto Stocchi, Caterina Ciacci, Piero Sestili
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/5152029