KHDC3L mutation causes recurrent pregnancy loss by inducing genomic instability of human early embryonic cells.

KHDC3L mutation causes recurrent pregnancy loss by inducing genomic instability of human early embryonic cells.

Recurrent pregnancy loss (RPL) is an important complication in reproductive health. About 50% of RPL cases are unexplained, and understanding the genetic basis is essential for its diagnosis and prognosis. Herein, we report causal KH domain containing 3 like (KHDC3L) mutations in RPL. KHDC3L is expr...

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Bibliographic Details
Main Authors: Weidao Zhang, Zhongliang Chen, Dengfeng Zhang, Bo Zhao, Lu Liu, Zhengyuan Xie, Yonggang Yao, Ping Zheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000468

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https://doi.org/10.1371/journal.pbio.3000468

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