The role of DNA double-strand breaks in spontaneous homologous recombination in S. cerevisiae.

The role of DNA double-strand breaks in spontaneous homologous recombination in S. cerevisiae.

Homologous recombination (HR) is a source of genomic instability and the loss of heterozygosity in mitotic cells. Since these events pose a severe health risk, it is important to understand the molecular events that cause spontaneous HR. In eukaryotes, high levels of HR are a normal feature of meios...

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Bibliographic Details
Main Authors: Gaëlle Lettier, Qi Feng, Adriana Antúnez de Mayolo, Naz Erdeniz, Robert J D Reid, Michael Lisby, Uffe H Mortensen, Rodney Rothstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1635536?pdf=render

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http://europepmc.org/articles/PMC1635536?pdf=render

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