MR spectroscopy-based brain metabolite profiling in propionic acidaemia: metabolic changes in the basal ganglia during acute decompensation and effect of liver transplantation

MR spectroscopy-based brain metabolite profiling in propionic acidaemia: metabolic changes in the basal ganglia during acute decompensation and effect of liver transplantation

<p>Abstract</p> <p>Background</p> <p>Propionic acidaemia (PA) results from deficiency of Propionyl CoA carboxylase, the commonest form presenting in the neonatal period. Despite best current management, PA is associated with severe neurological sequelae, in particular m...

Full description

Bibliographic Details
Main Authors: McKiernan Patrick J, Chakrapani Anupam, Sun Yu, Wilson Martin, Davies Nigel P, Davison James E, Walter John H, Gissen P, Peet Andrew C
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Orphanet Journal of Rare Diseases
Online Access:http://www.ojrd.com/content/6/1/19

Internet

http://www.ojrd.com/content/6/1/19

Similar Items