The Potential of the Combination of CRISPR/Cas9 and Pluripotent Stem Cells to Provide Human Organs from Chimaeric Pigs

The Potential of the Combination of CRISPR/Cas9 and Pluripotent Stem Cells to Provide Human Organs from Chimaeric Pigs

Clinical organ allotransplantation is limited by the availability of deceased human donors. However, the transplantation of human organs produced in other species would provide an unlimited number of organs. The pig has been identified as the most suitable source of organs for humans as organs of a...

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Bibliographic Details
Main Authors: Wanyou Feng, Yifan Dai, Lisha Mou, David K. C. Cooper, Deshun Shi, Zhiming Cai
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
CRISPR/Cas9
genome editing
iPSC
pigs
chimaeric
xenotransplantation
Online Access:http://www.mdpi.com/1422-0067/16/3/6545

Internet

http://www.mdpi.com/1422-0067/16/3/6545

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