Interference of the Zika Virus E-Protein With the Membrane Attack Complex of the Complement System

The complement system has developed different strategies to clear infections by several effector mechanisms, such as opsonization, which supports phagocytosis, attracting immune cells by C3 and C5 cleavage products, or direct killing of pathogens by the formation of the membrane attack complex (MAC)...

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Bibliographic Details
Main Authors: Zahra Malekshahi, Britta Schiela, Sarah Bernklau, Zoltan Banki, Reinhard Würzner, Heribert Stoiber
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.569549/full