Type I Diabetic Akita Mouse Model is Characterized by Abnormal Cardiac Deformation During Early Stages of Diabetic Cardiomyopathy with Speckle-Tracking Based Strain Imaging

Background/Aims: Diabetes mellitus (DM) has been demonstrated to have a strong association with heart failure. Conventional echocardiographic analysis cannot sensitively monitor cardiac dysfunction in type I diabetic Akita hearts, but the phenotype of heart failure is observed in molecular levels du...

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Main Authors: Yingchao Zhou, Hong Xiao, Jianfei Wu, Lingfeng Zha, Mengchen Zhou, Qianqian Li, Mengru Wang, Shumei Shi, Yanze Li, Liangkun Lyu, Qing Wang, Xin Tu, Qiulun Lu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:https://www.karger.com/Article/FullText/487690