PTSD is associated with accelerated transcriptional aging in World Trade Center responders

Abstract Posttraumatic stress disorder (PTSD) is associated with shortened lifespan and healthspan, which suggests accelerated aging. Emerging evidence suggests that methylation age may be accelerated in PTSD. It is important to examine whether transcriptional age is also accelerated because transcr...

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Bibliographic Details
Main Authors: Pei-Fen Kuan, Xu Ren, Sean Clouston, Xiaohua Yang, Katherine Jonas, Roman Kotov, Evelyn Bromet, Benjamin J. Luft
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01437-0