Using a medium of free amino acids to produce penicillin g acylase in fed-batch cultivations of Bacillus megaterium ATCC 14945

The production of penicillin G acylase (PGA, an important industrial enzyme) from a wild strain of Bacillus megaterium using a pool of free amino acids as substrate was studied in a bench-scale bioreactor. Experiments carried out in shakers showed that the substitution of casein for free amino acids...

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Bibliographic Details
Main Authors: R. G. Silva, V. R. Souza, E. R. Nucci, L. M. Pinotti, A. J. G. Cruz, R. C. Giordano, R. L.C. Giordano
Format: Article
Language:English
Published: Brazilian Society of Chemical Engineering 2006-03-01
Series:Brazilian Journal of Chemical Engineering
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-66322006000100005