Personalized computational model quantifies heterogeneity in postprandial responses to oral glucose challenge.

Plasma glucose and insulin responses following an oral glucose challenge are representative of glucose tolerance and insulin resistance, key indicators of type 2 diabetes mellitus pathophysiology. A large heterogeneity in individuals' challenge test responses has been shown to underlie the effe...

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Bibliographic Details
Main Authors: Balázs Erdős, Bart van Sloun, Michiel E Adriaens, Shauna D O'Donovan, Dominique Langin, Arne Astrup, Ellen E Blaak, Ilja C W Arts, Natal A W van Riel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008852