TKT maintains intestinal ATP production and inhibits apoptosis-induced colitis
Abstract Inflammatory bowel disease (IBD) has a close association with transketolase (TKT) that links glycolysis and the pentose phosphate pathway (PPP). However, how TKT functions in the intestinal epithelium remains to be elucidated. To address this question, we specifically delete TKT in intestin...
Main Authors: | , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-09-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-021-04142-4 |