Molecular patterns from a human gut-derived Lactobacillus strain suppress pathogenic infiltration of leukocytes into the central nervous system

Molecular patterns from a human gut-derived Lactobacillus strain suppress pathogenic infiltration of leukocytes into the central nervous system

Abstract Background Multiple sclerosis (MS) is an inflammatory demyelinating disease that affects 2.5 million people worldwide. Growing evidence suggests that perturbation of the gut microbiota, the dense collection of microorganisms that colonize the gastrointestinal tract, plays a functional role...

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Bibliographic Details
Main Authors: John Michael S. Sanchez, Daniel J. Doty, Ana Beatriz DePaula-Silva, D. Garrett Brown, Rickesha Bell, Kendra A. Klag, Amanda Truong, Jane E. Libbey, June L. Round, Robert S. Fujinami
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Neuroinflammation
Subjects:
Lactobacillus
Multiple sclerosis
Experimental autoimmune encephalomyelitis
Gut microbiota
Chemokines
Microbe-associated molecular patterns
Online Access:http://link.springer.com/article/10.1186/s12974-020-01959-2

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http://link.springer.com/article/10.1186/s12974-020-01959-2

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