Molecular Mechanisms Elicited by d-Aspartate in Leydig Cells and Spermatogonia

Molecular Mechanisms Elicited by d-Aspartate in Leydig Cells and Spermatogonia

A bulk of evidence suggests that d-aspartate (d-Asp) regulates steroidogenesis and spermatogenesis in vertebrate testes. This review article focuses on intracellular signaling mechanisms elicited by d-Asp possibly via binding to the N-methyl-d-aspartate receptor (NMDAR) in both Leydig cells, and spe...

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Bibliographic Details
Main Authors: Maria Maddalena Di Fiore, Alessandra Santillo, Sara Falvo, Salvatore Longobardi, Gabriella Chieffi Baccari
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:International Journal of Molecular Sciences
Subjects:
">D-aspartate
steroidogenesis
spermatogenesis
spermatogonia
Leydig cells
NMDAR
MAPK
STAR
PCNA
AURKB
Online Access:http://www.mdpi.com/1422-0067/17/7/1127

Internet

http://www.mdpi.com/1422-0067/17/7/1127

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