Histopathological Evaluation of Horse Serum-induced Immune Complex Vasculitis in Swine: Implication to Coronary Artery Lesions in Kawasaki Disease

Histopathological Evaluation of Horse Serum-induced Immune Complex Vasculitis in Swine: Implication to Coronary Artery Lesions in Kawasaki Disease

Immune complex (IC) vasculitis can be experimentally induced in animal models by intravenous injection of horse serum (HS), and the findings of HS-induced IC vasculitis in swine were very similar to that of Kawasaki disease (KD). The IC mechanism may be involved in the pathogenesis of vasculitis in...

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Bibliographic Details
Main Authors: Saji Philip, Wen-Chuan Lee, Mei-Hwan Wu, Cherian Kotturathu Mammen, Hung-Chi Lue
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Pediatrics and Neonatology
Subjects:
coronary artery lesions
histopathology
immune complex vasculitis
Kawasaki disease
two-dimensional echocardiography
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957213002325

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http://www.sciencedirect.com/science/article/pii/S1875957213002325

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