Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84

Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84

Abstract Background Medium-chain fatty acids and their 3-hydroxy derivatives are metabolites endogenously produced in humans, food-derived or originating from bacteria. They activate G protein-coupled receptors, including GPR84 and HCA3, which regulate metabolism and immune functions. Although both...

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Bibliographic Details
Main Authors: Anna Peters, Philipp Rabe, Petra Krumbholz, Hermann Kalwa, Robert Kraft, Torsten Schöneberg, Claudia Stäubert
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cell Communication and Signaling
Subjects:
HCAR
Hydroxycarboxylic acid receptors
GPR109b
GPCR
HCA3
GPR84
Online Access:http://link.springer.com/article/10.1186/s12964-020-0516-2

Internet

http://link.springer.com/article/10.1186/s12964-020-0516-2

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