The zonal evolution of collagen-network morphology quantified in early osteoarthritic grades of human cartilage

Summary: Objective: We aimed to directly quantify the zone-specific evolution in morphology of collagen fibers and networks in human cartilage during the progression of early osteoarthritis. Collagen fibers exhibit depth-dependent orientations and diameters crucial to their mechanical roles. Cartil...

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Bibliographic Details
Main Authors: Phoebe Szarek, Magnus B. Lilledahl, Nancy C. Emery, Courtland G. Lewis, David M. Pierce
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913120300777