Genetic Ablation of MiR-22 Fosters Diet-Induced Obesity and NAFLD Development

Genetic Ablation of MiR-22 Fosters Diet-Induced Obesity and NAFLD Development

miR-22 is one of the most abundant miRNAs in the liver and alterations of its hepatic expression have been associated with the development of hepatic steatosis and insulin resistance, as well as cancer. However, the pathophysiological roles of miR-22-3p in the deregulated hepatic metabolism with obe...

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Bibliographic Details
Main Authors: Monika Gjorgjieva, Cyril Sobolewski, Anne-Sophie Ay, Daniel Abegg, Marta Correia de Sousa, Dorothea Portius, Flavien Berthou, Margot Fournier, Christine Maeder, Pia Rantakari, Fu-Ping Zhang, Matti Poutanen, Didier Picard, Xavier Montet, Serge Nef, Alexander Adibekian, Michelangelo Foti
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Journal of Personalized Medicine
Subjects:
fatty liver disease
microRNAs
lipid metabolism
glycolysis
obesity
Online Access:https://www.mdpi.com/2075-4426/10/4/170

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https://www.mdpi.com/2075-4426/10/4/170

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