Pepsinogen C expression, regulation and its relationship with cancer
Abstract Pepsinogen C (PGC) belongs to the aspartic protease family and is secreted by gastric chief cells. PGC could be activated to pepsin C and digests polypeptides and amino acids, but as a zymogen PGC’s functions is unclear. In normal physiological conditions, PGC is initially detected in the l...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-05-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12935-017-0426-6 |