Pepsinogen C expression, regulation and its relationship with cancer

Abstract Pepsinogen C (PGC) belongs to the aspartic protease family and is secreted by gastric chief cells. PGC could be activated to pepsin C and digests polypeptides and amino acids, but as a zymogen PGC’s functions is unclear. In normal physiological conditions, PGC is initially detected in the l...

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Bibliographic Details
Main Authors: Shixuan Shen, Jingyi Jiang, Yuan Yuan
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Cancer Cell International
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12935-017-0426-6