Genetic and epigenetic differences of benign and malignant pheochromocytomas and paragangliomas (PPGLs)
Pheochromocytomas and paragangliomas (PPGLs) are tumors arising from the adrenal medulla and sympathetic/parasympathetic paraganglia, respectively. According to Th e Cancer Genome Atlas (TCGA), approximately 40% of PPGLs are due to germ line mutations in one of 16 susceptibility genes, and a further...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2018-01-01
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Series: | Endocrine Regulations |
Subjects: | |
Online Access: | https://doi.org/10.2478/enr-2018-0006 |