A facile one-pot synthesis of novel 2,5-disubstituted-1,3,4-oxadiazoles under conventional and microwave conditions and evaluation of their in vitro antimicrobial activities

A facile one-pot synthesis of novel 2,5-disubstituted-1,3,4-oxadiazoles under conventional and microwave conditions and evaluation of their in vitro antimicrobial activities

A rapid and efficient solvent-free synthesis of 2,5-disubstituted-1,3,4-oxadiazoles (3a–l) from fatty acid hydrazides (1a–f) under microwave irradiation is described. The structural elucidation of these compounds is based on their spectral data (IR, 1H NMR, 13C NMR and MS). All the newly synthesized...

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Bibliographic Details
Main Authors: Nida N. Farshori, Abdul Rauf, Maqsood A. Siddiqui, Ebtesam S. Al-Sheddi, Mai M. Al-Oqail
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Arabian Journal of Chemistry
Subjects:
2,5-Disubstituted-1,3,4-oxadiazoles
Conventional and microwave synthesis
Spectral data
Antimicrobial activities
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535213003808

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http://www.sciencedirect.com/science/article/pii/S1878535213003808

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