Multiple domain insertions and losses in the evolution of the Rab prenylation complex

<p>Abstract</p> <p>Background</p> <p>Rab proteins are regulators of vesicular trafficking, requiring a lipid modification for proper function, prenylation of C-terminal cysteines. This is catalysed by a complex of a catalytic heterodimer (Rab Geranylgeranyl Transferase...

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Bibliographic Details
Main Authors: Pereira-Leal Jose B, Rasteiro Rita
Format: Article
Language:English
Published: BMC 2007-08-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/7/140