Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infection.

Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infection.

Ectromelia virus (ECTV) causes mousepox in mice, a disease very similar to smallpox in humans. ECTV and variola virus (VARV), the agent of smallpox, are closely related orthopoxviruses. Mousepox is an excellent small animal model to study the genetic and immunologic basis for resistance and suscepti...

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Bibliographic Details
Main Authors: Isaac G Sakala, Geeta Chaudhri, Preethi Eldi, R Mark Buller, Gunasegaran Karupiah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4353717?pdf=render

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http://europepmc.org/articles/PMC4353717?pdf=render

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