Computational identification of diverse mechanisms underlying transcription factor-DNA occupancy.

ChIP-based genome-wide assays of transcription factor (TF) occupancy have emerged as a powerful, high-throughput method to understand transcriptional regulation, especially on a global scale. This has led to great interest in the underlying biochemical mechanisms that direct TF-DNA binding, with the...

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Bibliographic Details
Main Authors: Qiong Cheng, Majid Kazemian, Hannah Pham, Charles Blatti, Susan E Celniker, Scot A Wolfe, Michael H Brodsky, Saurabh Sinha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3731213?pdf=render