The small GTPase RhoA is required for proper locomotor circuit assembly.

The assembly of neuronal circuits during development requires the precise navigation of axons, which is controlled by attractive and repulsive guidance cues. In the developing spinal cord, ephrinB3 functions as a short-range repulsive cue that prevents EphA4 receptor-expressing corticospinal tract a...

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Bibliographic Details
Main Authors: Shalaka Mulherkar, Feng Liu, Qin Chen, Anjana Narayanan, Anthony D Couvillon, H David Shine, Kimberley F Tolias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3692541?pdf=render