Long Non-Coding RNAs: Key Regulators of Epithelial-Mesenchymal Transition, Tumour Drug Resistance and Cancer Stem Cells

Epithelial mesenchymal transition (EMT), the adoption by epithelial cells of a mesenchymal-like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and metastasis. In addition, it is becoming clear that is instrumental to both the development of drug resistance by tumou...

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Bibliographic Details
Main Authors: Richard Heery, Stephen P. Finn, Sinead Cuffe, Steven G. Gray
Format: Article
Language:English
Published: MDPI AG 2017-04-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/9/4/38