Standardisation of oxygen exposure in the development of mouse models for bronchopulmonary dysplasia

Progress in developing new therapies for bronchopulmonary dysplasia (BPD) is sometimes complicated by the lack of a standardised animal model. Our objective was to develop a robust hyperoxia-based mouse model of BPD that recapitulated the pathological perturbations to lung structure noted in infants...

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Bibliographic Details
Main Authors: Claudio Nardiello, Ivana Mižíková, Diogo M. Silva, Jordi Ruiz-Camp, Konstantin Mayer, István Vadász, Susanne Herold, Werner Seeger, Rory E. Morty
Format: Article
Language:English
Published: The Company of Biologists 2017-02-01
Series:Disease Models & Mechanisms
Subjects:
BPD
Online Access:http://dmm.biologists.org/content/10/2/185