Standardisation of oxygen exposure in the development of mouse models for bronchopulmonary dysplasia
Progress in developing new therapies for bronchopulmonary dysplasia (BPD) is sometimes complicated by the lack of a standardised animal model. Our objective was to develop a robust hyperoxia-based mouse model of BPD that recapitulated the pathological perturbations to lung structure noted in infants...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2017-02-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/10/2/185 |