Principles of meiotic chromosome assembly revealed in S. cerevisiae

During meiotic prophase chromosomes organise into a series of chromatin loops, but the mechanisms of assembly remain unclear. Here the authors use Saccharomyces cerevisiae to elucidate how this elaborate three-dimensional chromosome organisation is linked to genomic sequence, and demonstrate an esse...

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Bibliographic Details
Main Authors: Stephanie A. Schalbetter, Geoffrey Fudenberg, Jonathan Baxter, Katherine S. Pollard, Matthew J. Neale
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12629-0