Inhibitory Effects of Salinispora-derived Metabolites Against Multidrug Resistance: An In-silico Study

Background: Multi drug resistance (MDR) is known to defeat most chemotherapies as one of the main anticancer strategies. The role of overexpression or overactivation of ATP-binding cassette (ABC) transporters, especially P-glycoprotein (P-gp), in the development of chemotherapy has long been demonst...

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Bibliographic Details
Main Author: Morteza Ghandadi
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2020-07-01
Series:Pharmaceutical and Biomedical Research
Subjects:
Online Access:http://pbr.mazums.ac.ir/article-1-364-en.html