The γc family of cytokines: fine-tuning signals from IL-2 and IL-21 in the regulation of the immune response [version 1; referees: 3 approved]
Interleukin (IL)-2, IL-4, IL-7, IL-9, IL-15, and IL-21 form a family of cytokines based on the sharing of a receptor component, the common cytokine receptor γ chain, γc, which is encoded by the gene mutated in humans with X-linked severe combined immunodeficiency (XSCID). Together, these cytokines p...
Main Authors: | Rosanne Spolski, Daniel Gromer, Warren J. Leonard |
---|---|
Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2017-10-01
|
Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/6-1872/v1 |
Similar Items
-
STAT5 and CD4+ T Cell Immunity [version 1; referees: 4 approved]
by: David L. Owen, et al.
Published: (2017-01-01) -
Epigenetic and transcriptional control of mast cell responses [version 1; referees: 3 approved]
by: Silvia Monticelli, et al.
Published: (2017-11-01) -
Can follicular helper T cells be targeted to improve vaccine efficacy? [version 1; referees: 3 approved]
by: Michelle A. Linterman, et al.
Published: (2016-01-01) -
Recent advances in understanding basophil functions in vivo [version 1; referees: 5 approved]
by: David Voehringer
Published: (2017-08-01) -
Overexpression of angiotensin-converting enzyme in myelomonocytic cells enhances the immune response [version 1; referees: 3 approved]
by: Kenneth E. Bernstein, et al.
Published: (2016-03-01)