The γc family of cytokines: fine-tuning signals from IL-2 and IL-21 in the regulation of the immune response [version 1; referees: 3 approved]

The γc family of cytokines: fine-tuning signals from IL-2 and IL-21 in the regulation of the immune response [version 1; referees: 3 approved]

Interleukin (IL)-2, IL-4, IL-7, IL-9, IL-15, and IL-21 form a family of cytokines based on the sharing of a receptor component, the common cytokine receptor γ chain, γc, which is encoded by the gene mutated in humans with X-linked severe combined immunodeficiency (XSCID). Together, these cytokines p...

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Bibliographic Details
Main Authors: Rosanne Spolski, Daniel Gromer, Warren J. Leonard
Format: Article
Language:English
Published: F1000 Research Ltd 2017-10-01
Series:F1000Research
Subjects:
Autoimmunity
Immunity to Infections
Immunomodulation
Innate Immunity
Leukocyte Activation
Leukocyte Development
Leukocyte Signaling & Gene Expression
Online Access:https://f1000research.com/articles/6-1872/v1

Internet

https://f1000research.com/articles/6-1872/v1

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