Strengthening peptide-based drug activity with novel glyconanoparticle.

The therapeutic application of peptide-based drugs is significantly limited by the rapid proteolytic degradation that occurs when in blood. Encapsulation of these peptide structures within a delivery system, such as liposomes, can greatly improve both stability and target delivery. As part of our wo...

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Bibliographic Details
Main Authors: Jordan D Lewicky, Alexandrine L Martel, Nya L Fraleigh, Amanda Boraman, Thi M-D Nguyen, Peter W Schiller, Tze Chieh Shiao, René Roy, Hoang-Thanh Le
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6160049?pdf=render