The expanding universe of prion diseases.
Prions cause fatal and transmissible neurodegenerative disease. These etiological infectious agents are formed in greater part from a misfolded cell-surface protein called PrP(C). Several mammalian species are affected by the diseases, and in the case of "mad cow disease" (BSE) the agent h...
Format: | Article |
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Language: | English |
Published: |
Public Library of Science (PLoS)
2006-03-01
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Series: | PLoS Pathogens |
Online Access: | http://dx.doi.org/10.1371/journal.ppat.0020026 |