The expanding universe of prion diseases.

Prions cause fatal and transmissible neurodegenerative disease. These etiological infectious agents are formed in greater part from a misfolded cell-surface protein called PrP(C). Several mammalian species are affected by the diseases, and in the case of "mad cow disease" (BSE) the agent h...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-03-01
Series:PLoS Pathogens
Online Access:http://dx.doi.org/10.1371/journal.ppat.0020026