A PCR-mutagenesis strategy for rapid detection of mutations in codon 634 of the <it>ret</it> proto-oncogene related to MEN 2A.
<p>Abstract</p> <p>Background</p> <p>Multiple endocrine neoplasias type 2A (MEN 2A) is a dominantly inherited cancer syndrome. Missence mutations in the codon encoding cysteine 634 of the <it>ret</it> proto-oncogene have been found in 85% of the MEN 2A famil...
Main Authors: | Godoy Clara, Perinetti Héctor, Pusiol Eduardo, Roqué María, Mayorga Luis S |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2002-05-01
|
Series: | BMC Medical Genetics |
Online Access: | http://www.biomedcentral.com/1471-2350/3/4 |
Similar Items
-
A Vietnamese MEN2A syndrome patient with C634G germline mutation of the RET proto-oncogene
by: Pham Le Bich Hang, et al.
Published: (2019-12-01) -
The Role of the ret Proto-oncogene in Human Disease
by: Takahashi, Masahide
Published: (1997) -
The Ret proto-oncogene in the normal and transgenic thyroid
by: Reynolds, Lucinda Frances
Published: (1998) -
Multiple endocrine neoplasias type 2B and RET proto-oncogene
by: Martucciello Giuseppe, et al.
Published: (2012-03-01) -
Predicting phenotypic severity of uncertain gene variants in the RET proto-oncogene.
by: David K Crockett, et al.
Published: (2011-03-01)