A PCR-mutagenesis strategy for rapid detection of mutations in codon 634 of the <it>ret</it> proto-oncogene related to MEN 2A.
<p>Abstract</p> <p>Background</p> <p>Multiple endocrine neoplasias type 2A (MEN 2A) is a dominantly inherited cancer syndrome. Missence mutations in the codon encoding cysteine 634 of the <it>ret</it> proto-oncogene have been found in 85% of the MEN 2A famil...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2002-05-01
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Series: | BMC Medical Genetics |
Online Access: | http://www.biomedcentral.com/1471-2350/3/4 |