A PCR-mutagenesis strategy for rapid detection of mutations in codon 634 of the <it>ret</it> proto-oncogene related to MEN 2A.

<p>Abstract</p> <p>Background</p> <p>Multiple endocrine neoplasias type 2A (MEN 2A) is a dominantly inherited cancer syndrome. Missence mutations in the codon encoding cysteine 634 of the <it>ret</it> proto-oncogene have been found in 85% of the MEN 2A famil...

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Bibliographic Details
Main Authors: Godoy Clara, Perinetti Héctor, Pusiol Eduardo, Roqué María, Mayorga Luis S
Format: Article
Language:English
Published: BMC 2002-05-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/3/4