Physical effects of cholesterol on arterial smooth muscle membranes: evidence of immiscible cholesterol domains and alterations in bilayer width during atherogenesis

Physical effects of cholesterol on arterial smooth muscle membranes: evidence of immiscible cholesterol domains and alterations in bilayer width during atherogenesis

Small angle X-ray diffraction was used to examine arterial smooth muscle cell (SMC) plasma membranes isolated from control and cholesterol-fed (2%) atherosclerotic rabbits. A microsomal membrane enriched with plasma membrane obtained from animals fed cholesterol for up to 13 weeks showed a progressi...

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Bibliographic Details
Main Authors: Thomas N. Tulenko, Meng Chen, Pamela E. Mason, R. Preston Mason
Format: Article
Language:English
Published: Elsevier 1998-05-01
Series:Journal of Lipid Research
Subjects:
X-ray diffraction
membrane structure
atherosclerosis
phospholipids
heart disease
vascular disease
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033861X

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http://www.sciencedirect.com/science/article/pii/S002222752033861X

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