Ethanol and unsaturated dietary fat induce unique patterns of hepatic ω-6 and ω-3 PUFA oxylipins in a mouse model of alcoholic liver disease.

Ethanol and unsaturated dietary fat induce unique patterns of hepatic ω-6 and ω-3 PUFA oxylipins in a mouse model of alcoholic liver disease.

Alcoholic liver disease (ALD), a significant health problem, progresses through the course of several pathologies including steatosis, steatohepatitis, fibrosis, and cirrhosis. There are no effective FDA-approved medications to prevent or treat any stages of ALD, and the mechanisms involved in ALD p...

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Bibliographic Details
Main Authors: Dennis R Warner, Huilin Liu, Shubha Ghosh Dastidar, Jeffrey B Warner, Md Aminul Islam Prodhan, Xinmin Yin, Xiang Zhang, Ariel E Feldstein, Bin Gao, Russell A Prough, Craig J McClain, Irina A Kirpich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6157879?pdf=render

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http://europepmc.org/articles/PMC6157879?pdf=render

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